Oregonian: Dear Doctor: How does naltrexone work in treating those with alcohol use disorder?
Dear Doctor: How does naltrexone work in treating those with alcohol use disorder?
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Naltrexone blocks the euphoric and sedative effects of opioids such as heroin, morphine, and codeine. Naltrexone binds and blocks opioid receptors and reduces and suppresses opioid cravings. Naltrexone is not an opioid, is not addictive, and does not cause withdrawal symptoms with stop of use.
Due to this issue, the usefulness of oral naltrexone in opioid use disorder is limited by the low retention in treatment. Naltrexone taken orally remains an ideal treatment for a small number of people with opioid use, usually those with a stable social situation and motivation.
It works by decreasing the craving for alcohol and blocking the effects of opiate medications and opioid street drugs. How should this medicine be used? Naltrexone comes as a tablet to take by mouth either at home or under supervision in a clinic or treatment center.
What is naltrexone and what does it treat? Naltrexone is a medication that works in the brain to treat alcohol or opioid use disorders. Naltrexone works by blocking the effect of opioid receptors and decreasing cravings and urges to use alcohol or opioids.