Learn how to interpret your SDMA results for cats and dogs. Follow this algorithm to determine if kidney disease is probable and what steps you should take.
SDMA (symmetric dimethylarginine) is the amino acid, arginine, that contains two methyl groups (dimethyl) in a symmetrical orientation. SDMA is considered a sensitive and early marker (more sensitive than serum creatinine) of declining GFR in dogs and cats (Hokamp and Nabity 2016 review). Physiology SDMA is produced by all nucleated cells at a constant rate, […]
SDMA (Symmetric Dimethylarginine) is a kidney biomarker measured in cat bloodwork. Normal SDMA in cats is 0–14 µg/dL. Values of 15–17 µg/dL are borderline and indicate early CKD risk; 18 µg/dL or higher indicates IRIS Stage 2 kidney disease. SDMA detects kidney problems when only 25–40% of function is lost — up to 2 years before creatinine rises.
High SDMA in Cats: What 15, 18, or 25+ µg/dL Actually Means
SDMA is a blood marker that can detect kidney disease in cats earlier than traditional tests, giving you more time to act.
Learn about high SDMA levels in cats, their causes, and potential health concerns. Understand symptoms, diagnosis, and treatment options for your feline friend.
Learn how to interpret your SDMA results Any increase in SDMA concentration above the reference interval (greater than 14 µ g/dL in cats and adult dogs; greater than 16 µ g/dL in puppies) is considered meaningful. An elevated SDMA concentration is a reflection of impaired glomerular filtration rate (GFR). Both primary kidney disease and secondary kidney insults, such as concurrent disease ...
Learn about SDMA in cats, its causes, symptoms, and treatment options. Understand how to prevent or manage this feline health issue with expert advice on diet, lifestyle changes, and medications.